β–Nicotinamide Mononucleotide (NMN): Cellular Energy & Longevity Molecule
β–Nicotinamide Mononucleotide (NMN) is a direct precursor to NAD⁺ (nicotinamide adenine dinucleotide), a vital coenzyme that powers cellular metabolism, mitochondrial function, and DNA repair. As NAD⁺ levels naturally decline with age, NMN supplementation has gained prominence for its ability to restore NAD⁺ availability—supporting healthy aging at the cellular level. NMN is one of the most promising ingredients in the field of nutrigerontology and is a key nutrient for anyone focused on long-term vitality.
Replenishing NAD⁺ for Energy and Repair
NAD⁺ is essential for converting food into cellular energy (ATP) and activating enzymes involved in cell repair and stress resistance. NMN supplementation increases intracellular NAD⁺ levels, helping maintain mitochondrial performance, metabolic balance, and cellular resilience. These effects are particularly important as age-related NAD⁺ decline is linked to fatigue, slower recovery, and systemic aging.
Sirtuin Activation and Longevity Pathways
NMN-driven NAD⁺ production supports the activation of sirtuins—cellular regulators involved in gene expression, inflammation control, and DNA repair. Sirtuins like SIRT1 and SIRT3 are closely associated with caloric restriction mimetics and lifespan extension. NMN’s role in stimulating these pathways positions it as a foundational compound in science-based longevity stacks.
Neuroprotection and Vascular Health
Animal and early human studies suggest NMN may support cognitive performance, neurovascular integrity, and blood flow regulation. By promoting NAD⁺-dependent processes in neurons and endothelial cells, NMN helps preserve brain function, memory, and circulatory efficiency—key components of aging well.
Bioavailability and Clinical-Grade Purity
Our NMN is formulated for maximum bioavailability and stability, using pharmaceutical-grade β–NMN with third-party testing for purity and identity. It is rapidly absorbed and utilized by the body without the conversion delays of earlier NAD⁺ precursors. Taken daily, NMN offers a safe and effective strategy to counteract age-related NAD⁺ depletion and support cellular rejuvenation.
References
- Mills, K. F., et al. (2016). “Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice.” Cell Metabolism, 24(6), 795–806.
- Yoshino, J., et al. (2021). “Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women.” Science, 372(6547), 1224–1229.
- Imai, S., & Guarente, L. (2014). “NAD+ and sirtuins in aging and disease.” Trends in Cell Biology, 24(8), 464–471.
